Welcome to SIKO Pharma GmbH!
SIKO Pharma GmbH new to the pharmaceutical market

Since April 1, 2010, SIKO Pharma has been operating as a newly founded GmbH in Vienna. The managing partner Mag. (FH) Eva Köstenberger, together with her father, Mag. Siegfried Köstenberger, continues the tradition and the concept of SiKo-Pharma, which was founded 4 years ago, in the new corporation. Among other things, it relies on the  marketing of well-established drugs and medical products from well-known pharmaceutical companies.

„When pharmaceutical companies   think of outsourcing products in order to extend the  life cycle of their pharmaceuticals , SIKO Pharma GmbH is the right partner“, Mag. (FH) Eva Köstenberger formulates her business idea. „Both partners benefit from this concept: the drugs and sales remain with the authorization holder, SIKO Pharma GmbH receives a commission from the additional sales realized for the services provided“.

The neo-entrepreneur looks back on 5 years of pharmaceutical know-how at Mundipharma, Pfizer and Eli Lilly and also has experience in advertising agencies. With its own  field service  of independent pharmaceutical representatives with many years of experience and corresponding  marketing and PR activities,  the company advertises the products to doctors in private practice, in hospitals and also in pharmacies.

SIKO Pharma aims to  focus  initially on the following therapeutic areas:  Sclerotherapy  (sclerotherapy for spider veins and varicose veins) | Wound management  with medicinal honey | Bronchial asthma  and  COPD  (chronic obstructive pulmonary disease) | Thromboembolism prophylaxis  using low molecular weight heparin | Compression therapy  with medical compression and support stockings.

Press release (06.2013):
Thrombosis prophylaxis with Gloria support stockings.

Press release (01.2012):
Compression and support stockings from Gloria.

Press release (11.2011):
Foam sclerotherapy in varicose veins.

Press release (09.2010):
GSK cooperates with SIKO Pharma GmbH in the field of asthma and COPD therapy.

Press release (04.2010):
Founding of SIKO Pharma GmbH. SIKO Pharma is also open in the future to  new collaborations with pharmaceutical companies that  do not want to do without products that have been tried and tested over many years and  want to outsource  marketing and advertising to other competent hands. New, innovative drugs can also be marketed by SIKO Pharma GmbH.

to the CE-certified medical products DerMel ®  wound  ointment and NasuMel ® nasal ointment for wound treatment!
The Dutch medicinal honey has been sold on the Austrian market by SIKO Pharma GmbH since 2009. The products are available in all pharmacies (mostly by order). Alternatively, you can order these quickly and easily  online  from home at  APOdirekt.at  or  shop-apotheke.at  :
ORDER POSSIBILITIES  of  Dermel ®  wound  and  NasuMel ®  nasal ointment:
→ Reserve the product online and  pick it up at the  pharmacy near you! Click here:  APOdirekt.at-rgb-1-

→ order the product online, the  delivery  in  2-4 days by mail  received! Click here:

Application areas:
The products consist of a  skin-nourishing ointment  in combination with  pure, enzyme-rich honey  and are suitable for babies, children and adults.
  • The Mel ®  Wound Ointment  15g / 30g can be used for the care, protection and healing of  irritated, dry  and / or  sensitive skin  (e.g. with eczema). DerMel ®  is also suitable for the treatment of  superficial  and  inflamed wounds  (caused, for example, by scratching eczema). The specific composition (including low pH value) strengthens the skin’s natural defenses. When applied to the skin, DerMel ® has  a slightly cooling effect and  reduces itching.
  • NasuMel ®  nasal ointment  15g can be used to treat wounds  in the nose  and for  dry, damaged  and  inflamed nasal mucous membranes  as well as for  cracks  in the nose. NasuMel ®  helps prevent the  formation of crusts  in the nose. Thanks to its specific composition, NasuMel ® protects  superficial wounds from infections.


→  DerMel ® and NasuMel ®  are antibacterial  but free of  antibiotics, anti-inflammatory  but  free of cortisone, wound healing  but  free of chemicals! → Medicinal honey helps the skin heal!

B reites spectrum of the Medical-honey in wound management:

  • The antibacterial effect is seen as one of the most important roles of honey in the wound healing process. Honey contains the  enzyme glucose oxidase.  This is activated by diluting the honey with the wound secretion. This creates small amounts of hydrogen peroxide, which is responsible for the  germicidal effect  . The long enzyme action effectively kills harmful bacteria and disinfects the wound.
    • Enzyme effect of glucose oxidase:  In a colony, thousands of honey bees work together to process the sugary nectar obtained from the flowers into honey. When the honey is “ripe”, it is stored in sealed honey cells.
    • During the thickening of the nectar into honey, the bees add  various enzymes  . One of them is glucose oxidase. This enzyme activates the gradual conversion of honey sugar (glucose) into gluconic acid and hydrogen peroxide.
    • If the honey comes into contact with moisture, for example in a wound, the enzyme is activated. This gradual production of hydrogen peroxide has a  disinfecting effect , while the gluconic acid formed forms an acidic wound environment, which inhibits  bacterial growth  .
  • The high sugar concentration in honey removes moisture from the germs (osmotic potential), flushing harmful substances out of the wound, cleaning the  wounds and  restricting  the  activity  and reproduction of bacteria  .
  • The foul smell of infected wounds usually indicates a bacterial overgrowth. By changing the bacterial metabolism and reducing the number of bacteria, honey has an odor- reducing effect  .

→ Medicinal honey works against aerobic, anaerobic, gram-positive and gram-negative bacteria, problem germs, fungi and viruses.

Increasing  resistance of bacteria to antibiotics is  leading to a  renaissance  of wound treatment with medicinal honey, as no honey-resistant germs have been  discovered so far  .



  • Inflammation is a sign of a defensive reaction in the body. Honey’s anti-inflammatory effects result from the  elimination of bacteria  and can be partly explained by the presence of flavonoids derived from nectar and pollen.
  • Flavonoids have a powerful  antioxidant effect, meaning they scavenge harmful oxygen radicals  . A relatively large number of inflammatory cells are present in chronic wounds. These cells produce oxygen radicals, among other things, which makes the wound restless and painful. Chronic wounds  calm down after using honey and can then move into the proliferation phase. Research shows that honey also stimulates the production of anti-inflammatory cytokines in the wound.

→ When honey is applied, signs of inflammation such as pain, swelling, redness and edema can be significantly reduced.


The hydrophilic properties, the low pH value and water content and the high sugar concentration of honey create a  moist wound environment. The flow of fluid cleans the wound and protects against new infections. Honey applied to wounds promotes tissue regeneration during the various phases of wound healing  , which has a positive effect on wound healing, wounds close and can heal.
→ Medicinal honey supports the wound healing process.

Patient case  „Therapy of a pressure ulcer with  image documentation  for wound healing“: Patient case DerMel 06.12

Manufacture of medicinal honey in Holland:
The manufacturer Bfactory Health Products BV, together with the University of Wageningen in Holland, has developed a type of honey that is specially designed for the treatment of wounds. DerMel ®  and NasuMel ®  are produced in Holland under  controlled conditions in greenhouses  without the use of pesticides and chemicals. The process was developed in such a way that it is known exactly what nectar the bees are collecting.

Bees do not come into contact with pesticide-contaminated plants during honey production. In addition, bee colonies with excellent health are used, which means that there are no diseases in the bee colonies and consequently no control agents have to be used. A healthy and strong beehive produces honey with a high enzyme content.

All of this leads to a residue-free honey with a reproducible  high enzyme content  and a  low pH value . Before the honey is processed, it is  pressed through ultra-fine  filters to remove a large part of the pollen. It is also sterilized with  gamma rays  , which does not destroy the enzymes involved in healing. It is checked for enzyme content, pH value, acid and water content. Only honey batches that  meet all  quality requirements are used for production. → DerMel ®  and NasuMel ®
 contain no antibiotics, cortisone, preservatives or residues of pesticides and no substances known to cause allergic reactions.


Ingredients  of  DerMel and NasuMel ® peanut oil, white beeswax, glyceryl oleate, honey, water. Use during pregnancy or breastfeeding: There are no indications that DerMel  Wound Ointment should not be used during pregnancy or breastfeeding When should DerMel  NasuMel  not be used? If you are hypersensitive to any component of the ointment (see ingredients). Side effects: A slight burning sensation can be caused in the first few minutes after application. This disappears after a few minutes and is no reason to stop treatment. In the event of unexpected (not mentioned here) side effects during use, please contact your doctor or pharmacist.

Medicinal honey is not honey from the supermarket shelf:

honey has it all – in a positive sense. It was used in wound treatment more than 4,000 years ago   . Natural honey as we know it is not suitable for today’s wound treatment. Medicinal honey for wound care is subject to  strict controls  and must meet  highly specific standards in  terms of  purity, effectiveness and biological safety  , which leads to consistently high quality. Only enzyme-rich, specially purified and enzyme-rich honey is used for use on the skin.
→ DerMel ®  and NasuMel ® meet the criteria and are approved as CE-certified medical products.


brochure  :  A brochure including a discount voucher is available here for  information about wound care with medicinal honey on  delicate children’s skin: Patient brochure

availability : The products can be  ordered at  apodirekt.at , are listed in pharmacies (PHZNR: DerMel Wundsalbe 30g: 3282074 | DerMel Wundsalbe 15g: 3813206 | NasuMel Nasal Ointment 15g: 3282080) and can be ordered for you to collect.

Product order  of  DerMel  wound  and  NasuMel  nasal ointment:
→ Reserve the product online and pick it up at the pharmacy near you! Click here:  APOdirekt.at-rgb-1-
→ Order the product online and receive it by post in 2-4 days! Click here